A new species of Anadia (Reptilia, Squamata) from the Venezuelan 'Lost World', northern South America

A new gymnophthalmid lizard of the genus Anadia Gray, 1845 is described from the summit of Abakapá-tepui, Bolívar State, Venezuela, between 2200-2242 m elevation. The new species, Anadia mcdiarmidi sp. nov., is endemic to the Chimantá Massif and seemingly also occurs on Amurí-tepui and Murei-tepui. The new taxon is mainly distinguished from all known congeners by the following combination of characters: body fairly robust, dorsal scales small and quadrangular, middorsal scales 53-57, suboculars large, subequal in size, with sometimes one scale slightly protruding downward between 4th and 5th supralabial, nasal entire, without sub-nostril groove, body uniform beige or greyish to bluish brown in life, devoid of any conspicuous pattern in males, venter immaculate golden grey in life, femoral pores 9-10 on each side in males, preanal pores absent, hemipenis globose, weakly bilobed, bordered by numerous fl ounces (>20) bearing comblike rows of minute weakly mineralized spinules. The presence of a species of Anadia, a primarily Andean genus, on the top of tepuis is of considerable interest to the understanding of the Pantepui biogeography

The exact three-dimensional half-shell t-matrix for a sharply cut-off Coulomb potential in the screening limit

The three-dimensional half-shell t-matrix for a sharply cut-off Coulomb potential is analytically derived together with its asymptotic form without reference to partial wave expansion. The numerical solutions of the three-dimensional Lippmann-Schwinger equation for increasing cut-off radii provide half-shell t-matrices which are in quite a good agreement with the asymptotic values.Comment: 15 pages, 4 eps figure

Influence of sildenafil on blood oxygen saturation of the obstructed bladder

Background: Blood oxygen saturation (BOS) is decreased in a low-compliant, overactive obstructed bladder. The objective of this study is to determine the effect of Sildenafil (SC) on bladder function and BOS) in an in vivo animal model of bladder outlet obstruction. Methods. Thirty-two guinea pigs; sham operated (n = 8), sham operated + SC (n = 8), urethrally obstructed (n = 8) and urethrally obstructed + SC (n = 8) were studied during an 8 week period. BOS of the bladder wall was measured by differential path-length spectroscopy (DPS) before obstruction, at day 0, and at week 8. The bladder function was evaluated by urodynamic studies every week. Results: Before surgery and after sham operation all study parameters were comparable. After sham operation, bladder function and BOS did not change. In the obstructed group the urodynamic parameters were deteriorated and BOS was decreased. In the group obstruction + SC, bladder compliance remained normal and overactivity occurred only sporadic. BOS remained unchanged compared to the sham group and was significantly higher compared to the obstruction group. Conclusions: In an obstructed bladder the loss of bladder function is accompanied by a significant decrease in BOS. Treatment of obstructed bladders with SC yields a situation of high saturation, high bladder compliance and almost no overactivity. Maintaining the microcirculation of the bladder wall might result in better bladder performance without significant loss of bladder function. Measurement of BOS and interventions focussing on tissue microcirculation may have a place in the evaluation / treatment of various bladder dysfunctions

A new genus of Cophomantini, with comments on the taxonomic status of Boana liliae (Anura: Hylidae)

© 2018 The Linnean Society of London The non-monophyly of both the genus Myersiohyla and the Boana punctata group has been recovered in a number of published phylogenetic analyses. In this paper we report on the analysis of sequences of Boana liliae, a species originally assigned to the B. punctata group, in a dataset of Cophomantini that recovered novel phylogenetic relationships for this hylid tribe. Our results reveal Myersiohyla to be paraphyletic with respect to B. liliae. Support for the placement of Myersiohyla kanaima is poor, but this taxon is recovered as the sister taxon of the other Cophomantini genera (excluding Myersiohyla) or as the sister taxon of the remaining species of Myersiohyla (including B. liliae). These results lead us to propose two taxonomic changes in order to remedy the paraphyly of Myersiohyla: (1) a new genus is described for M. kanaima, and (2) Boana liliae is transferred to Myersiohyla. We further provide notes on the natural history and vocalizations of the new monotypic genus, a new diagnosis of the former B. liliae in the context of Myersiohyla, and discuss the evolution of tadpole morphology and biogeography of the earlier diverging clades of Cophomantini

Information fusion in multi-agent system based on reliability criterion

The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-319-00369-6_13The paper addresses the problem of information fusion in Multi-Agent System. Since the knowledge of the process state is distributed between agents, the efficiency of the task performance depends on a proper information fusion technique applied to the agents. In this paper we study the case in which each agent has its own sensing device and is able to collect information with some certainty. Since the same information can be detected by multiple agents, the global certainty about the given fact derives from the fusion of information exchanged by interconnecting agents. The key issue in the method proposed, is an assumption that each agent is able to asses its own reliability during the task performance. The method is illustrated by the pick-up-and-collection task example. The effectiveness of the method proposed is evaluated using relevant simulation experiments.Mellado Arteche, M.; Skrzypczyk, K. (2013). Information fusion in multi-agent system based on reliability criterion. En Vision Based Systemsfor UAV Applications. Springer. 207-217. doi:10.1007/978-3-319-00369-6_13S207217Cheng, X., Shen, J., Liu, H., Gu, G.: Multi-robot Cooperation Based on Hierarchical Reinforcement Learning. In: Shi, Y., van Albada, G.D., Dongarra, J., Sloot, P.M.A. (eds.) ICCS 2007, Part III. LNCS, vol. 4489, pp. 90–97. Springer, Heidelberg (2007)Harmati, I., Skrzypczyk, K.: Robot team coordination for target tracking using fuzzy logiccontroller in game theoretic framework. Robotics and Autonomous Systems 57(1) (2009)Jones, C., Mataric, M.: Adaptive Division of Labor in Large-Scale Minimalist Multi-Robot Systems. In: Proc. of IEEE/RSJ International Conference on Intelligent Robots and Systems, Las Vegas, pp. 1969–1974 (2003)Kaminka, G.A., Erusalimchik, D., Kraus, S.: Adaptive Multi-Robot Coordination: A Game-Theoretic Perspective. In: Proc. of IEEE International Conference on Robotics and Automation, Anchorage Convention District, Anchorage, Alaska, USA (2002)Kok, J.R., Spaan, M.T.J., Vlassis, N.: Non-communicative multi-robot coordination in dynamic environments. Robotics and Autonomous Systems 50(2-3), 99–114 (2005)Klusch, M., Gerber, A.: Dynamic coalition formation among rational agents. IEEE Intelligent Systems 17(3), 42–47 (2002)Kraus, S., Winkfeld, J., Zlotkin, G.: Multiagent negotiation under time constraints. Artificial Intelligence 75, 297–345 (1995)Kraus, S.: Negotiation and cooperation in multiagent environments. Artificial Intelligence 94(1-2), 79–98 (1997)Mataric, M., Sukhatme, G., Ostergaard, E.: Multi-Robot Task Allocation in Uncertain Environments. Autonomous Robots 14, 255–263 (2003)Schneider-Fontan, M., Mataric, M.J.: Territorial Multi-Robot Task Division. IEEE Transactionson Robotics and Automation 14(5), 815–822 (1998)Winkfeld, K.J., Zlotkin, G.: Multiagent negotiation under time constraints. Artificial Intelligence (75), 297–345 (1995)Wooldridge, M.: An Introduction to Multiagent Systems. Johnn Wiley and Sons Ltd., UK (2009) ISBN:978-0-470-51946-2Vail, D., Veloso, M.: Dynamic Multi-Robot Coordination. In: Schultz, A., et al. (eds.) Multi Robot Systems: From Swarms to Intelligent Automata, vol. II, pp. 87–98. Kluwer Academic Publishers, The Netherlands (2003)Gałuszka, A., Pacholczyk, M., Bereska, D., Skrzypczyk, K.: Planning as Artifficial Intelligence Problem-short introduction and overview. In: Nawrat, A., Simek, K., Świerniak, A. (eds.) Advanced Technologies for Intelligent Systems of National Border Security. SCI, vol. 440, pp. 95–104. Springer, Heidelberg (2013)Jędrasiak, K., Bereska, D., Nawrat, A.: The Prototype of Gyro-Stabilized UAV Gimbal for Day-Night Surveillance. In: Nawrat, A., Simek, K., Świerniak, A. (eds.) Advanced Technologies for Intelligent Systems of National Border Security. SCI, vol. 440, pp. 107–116. Springer, Heidelberg (2013)Galuszka, A., Bereska, D., Simek, K., Skrzypczyk, K., Daniec, K.: Application of graphs theory methods to criminal analysis system. Przeglad Elektrotechniczny 86(9), 278–283 (2010

Linear stability analysis of transverse dunes

Sand-moving winds blowing from a constant direction in an area of high sand availability form transverse dunes, which have a fixed profile in the direction orthogonal to the wind. Here we show, by means of a linear stability analysis, that transverse dunes are intrinsically unstable. Any along-axis perturbation on a transverse dune amplify in the course of dune migration due to the combined effect of two main factors, namely: the lateral transport through avalanches along the dune's slip-face, and the scaling of dune migration velocity with the inverse of the dune height. Our calculations provide a quantitative explanation for recent observations from experiments and numerical simulations, which showed that transverse dunes moving on the bedrock cannot exist in a stable form and decay into a chain of crescent-shaped barchans.Comment: 8 pages, 4 figure

Dynamic Partition of Collaborative Multiagent Based on Coordination Trees

In team Markov games research, it is difficult for an individual agent to calculate the reward of collaborative agents dynamically. We present a coordination tree structure whose nodes are agent subsets or an agent. Two kinds of weights of a tree are defined which describe the cost of an agent collaborating with an agent subset. We can calculate a collaborative agent subset and its minimal cost for collaboration using these coordination trees. Some experiments of a Markov game have been done by using this novel algorithm. The results of the experiments prove that this method outperforms related multi-agent reinforcement-learning methods based on alterable collaborative teams

Scale-free memory model for multiagent reinforcement learning. Mean field approximation and rock-paper-scissors dynamics

A continuous time model for multiagent systems governed by reinforcement learning with scale-free memory is developed. The agents are assumed to act independently of one another in optimizing their choice of possible actions via trial-and-error search. To gain awareness about the action value the agents accumulate in their memory the rewards obtained from taking a specific action at each moment of time. The contribution of the rewards in the past to the agent current perception of action value is described by an integral operator with a power-law kernel. Finally a fractional differential equation governing the system dynamics is obtained. The agents are considered to interact with one another implicitly via the reward of one agent depending on the choice of the other agents. The pairwise interaction model is adopted to describe this effect. As a specific example of systems with non-transitive interactions, a two agent and three agent systems of the rock-paper-scissors type are analyzed in detail, including the stability analysis and numerical simulation. Scale-free memory is demonstrated to cause complex dynamics of the systems at hand. In particular, it is shown that there can be simultaneously two modes of the system instability undergoing subcritical and supercritical bifurcation, with the latter one exhibiting anomalous oscillations with the amplitude and period growing with time. Besides, the instability onset via this supercritical mode may be regarded as "altruism self-organization". For the three agent system the instability dynamics is found to be rather irregular and can be composed of alternate fragments of oscillations different in their properties.Comment: 17 pages, 7 figur

The ANTARES Optical Beacon System

ANTARES is a neutrino telescope being deployed in the Mediterranean Sea. It consists of a three dimensional array of photomultiplier tubes that can detect the Cherenkov light induced by charged particles produced in the interactions of neutrinos with the surrounding medium. High angular resolution can be achieved, in particular when a muon is produced, provided that the Cherenkov photons are detected with sufficient timing precision. Considerations of the intrinsic time uncertainties stemming from the transit time spread in the photomultiplier tubes and the mechanism of transmission of light in sea water lead to the conclusion that a relative time accuracy of the order of 0.5 ns is desirable. Accordingly, different time calibration systems have been developed for the ANTARES telescope. In this article, a system based on Optical Beacons, a set of external and well-controlled pulsed light sources located throughout the detector, is described. This calibration system takes into account the optical properties of sea water, which is used as the detection volume of the ANTARES telescope. The design, tests, construction and first results of the two types of beacons, LED and laser-based, are presented.Comment: 21 pages, 18 figures, submitted to Nucl. Instr. and Meth. Phys. Res.

Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation

Disruption to protein homeostasis caused by lysosomal dysfunction and associated impairment of autophagy is a prominent pathology in amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). The most common genetic cause of ALS/FTD is a G4C2 hexanucleotide repeat expansion in C9orf72 (C9ALS/FTD). Repeat-associated non-AUG (RAN) translation of G4C2 repeat transcripts gives rise to dipeptide repeat (DPR) proteins that have been shown to be toxic and may contribute to disease etiology. Genetic variants in TMEM106B have been associated with frontotemporal lobar degeneration with TDP-43 pathology and disease progression in C9ALS/FTD. TMEM106B encodes a lysosomal transmembrane protein of unknown function that is involved in various aspects of lysosomal biology. How TMEM106B variants affect C9ALS/FTD is not well understood but has been linked to changes in TMEM106B protein levels. Here, we investigated TMEM106B function in the context of C9ALS/FTD DPR pathology. We report that knockdown of TMEM106B expression exacerbates the accumulation of C9ALS/FTD-associated cytotoxic DPR proteins in cell models expressing RAN-translated or AUG-driven DPRs as well as in C9ALS/FTD-derived iAstrocytes with an endogenous G4C2 expansion by impairing autophagy. Loss of TMEM106B caused a block late in autophagy by disrupting autophagosome to autolysosome maturation which coincided with impaired lysosomal acidification, reduced cathepsin activity, and juxtanuclear clustering of lysosomes. Lysosomal clustering required Rab7A and coincided with reduced Arl8b-mediated anterograde transport of lysosomes to the cell periphery. Increasing Arl8b activity in TMEM106B-deficient cells not only restored the distribution of lysosomes, but also fully rescued autophagy and DPR protein accumulation. Thus, we identified a novel function of TMEM106B in autophagosome maturation via Arl8b. Our findings indicate that TMEM106B variants may modify C9ALS/FTD by regulating autophagic clearance of DPR proteins. Caution should therefore be taken when considering modifying TMEM106B expression levels as a therapeutic approach in ALS/FTD